|Research groups||Involvement in the project activities|
|Biochemistry & eco-toxicology
Group leader Vasile OSTAFE
|Developing and evaluating methods to assess the potential risks of organic chemicals to humans and the environment
Developing metabolic biotransformation and biodegradation rate estimation methods
Human exposure to xenobiotics and health assessment
Advanced scientific research on chitin/chitosan, including studies on its structure, biomaterials, biotechnology as well as applications
Developing protocols for analysis of complex mixtures of compounds (chemical fingerprinting)
|Toxicity testing and safety assessment of substances
Environmental biodegradation control of polymers
Ecotoxicity testing methods applied on soil and water microflora
Environmental hazard assessment for engineered nanoparticles
|Ecotoxicology at organism level
Bianca Vanesa BOROS
|Techniques for determination of ecotoxicity on low level organisms for various types of chemicals: growth inhibition test on aquatic and terrestrial plants, acute toxicity test on aquatic and terrestrial animals|
|Environmental and analytical chemistry
|Techniques for determination of ecotoxicity at molecular level for various types of chemicals: enzyme activity assays, ecotoxicological test batteries|
|Engineering transcription & metabolic networks
Enzymatic hydrolysis of chitin and chitosan
Enzyme-based strategies aiming for selective and efficient routes towards functional bio-based polymers
Innovative enzyme solutions for efficient biomass utilization – environmentally friendly technologies for the production of biofuels, chemicals, and materials from biomass resources
Mimic Nature and alter the catalytic machinery so that new chemical reactions can be performed in new enzymes’ active site
Selective enzyme catalysis to obtain desired products
|Advanced Computational Chemistry (Biophysics & Bioinformatics)
Group leader Adriana ISVORAN
|Applications of computational chemistry methods in determining the structure, ADMNE-Tox and pharmacokinetics profiles of small to middle size molecules.
Structural bioinformatics – proteins structure analysis and characterization, protein surface characterization, homology modelling.
Computational analysis of protein-protein and protein-ligand interactions.
Protein and membrane dynamics.
Fractal aspects of protein structure.
Non-linear dynamics of biopolymers.
|Chemoinformatics for establishing the ADMNE-Tox properties of biologic active compound, prediction of their activity, molecular targets and side effects/toxicity.
|Chemoinformatics for establishing the ADMNE-Tox properties of biologic active compound, prediction of their activity, molecular targets and side effects/toxicity.|
|Environmental Monitoring and Analysis Technology / Water & Air Quality
Group leader Dana DASCĂLU
|Chitin/chitosan derivatives for corrosion protection and waste water treatments
Designing transdermal delivery systems for various polymeric nanobiomaterials
Toxicity evaluation of biodegradable nanomaterials; experimental analysis of the physico-chemical factors that influence toxicity
Development and validation of accurate protocols regarding material characterization and toxicity prediction