Published scientific articles
Matica A.; Menghiu G.; Ostafe V. Antibacterial Properties of Chitin and Chitosans. New Frontiers in Chemistry 2017, 26, 39-54. 
Matica A.; Menghiu G.; Ostafe V. Antifungal Properties of Chitosans. New Frontiers in Chemistry 2017, 26, 55-63.
Matica A.; Menghiu G.; Ostafe V. Toxicity of Chitosan Based Products. New Frontiers in Chemistry 2017, 26, 65-74.
Matica A.; Menghiu G.; Ostafe V. Biodegradability of Chitosan Based Products. New Frontiers in Chemistry 2017, 26, 75-86.
Moraru C, Mincea M, Frandes M, Timar B, Ostafe V, „A meta-analysis evaluating the effect of the dietary supplement chitosan on some parameters connected with body weight decrease”, Medicina, 2018, 54, 109; doi:10.3390/medicina54060109
Conference presentations
| Title of scientific event: BioNanoMaterials used in medical applications |
| Period: 21 March 2019 |
| Location: West University of Timisoara (Advanced Environmental Research Laboratories), Timisoara (Romania) |
| Link to event: http://gonanobiomat.eu/results/workshops/ |
| Title of the presented work: Polymeric NanoBioMaterials for drug delivery: developing and implementation of safe-by-design concept enabling safe healthcare solution |
| List of authors: Vasile OSTAFE |
| Title of scientific event: BioNanoMaterials used in medical applications |
| Period: 21 March 2019 |
| Location: West University of Timisoara (Advanced Environmental Research Laboratories), Timisoara (Romania) |
| Link to event: http://gonanobiomat.eu/results/workshops/ |
| Title of the presented work: Computational assessment of interactions between chito-oligomers and plasma proteins |
| List of authors: Diana Larisa ROMAN, Vasile OSTAFE, Adriana ISVORAN |
| Title of scientific event: BioNanoMaterials used in medical applications |
| Period: 21 March 2019 |
| Location: West University of Timisoara (Advanced Environmental Research Laboratories), Timisoara (Romania) |
| Link to event: http://gonanobiomat.eu/results/workshops/ |
| Title of the presented work: Prediction of the ADME-Tox profiles of oligomers of 4-hydroxybutyric acid and 4-hydroxyvaleric acid |
| List of authors: Mădălina FILIP, Vasile OSTAFE, Adriana ISVORAN |
| Title of scientific event: BioNanoMaterials used in medical applications |
| Period: 21 March 2019 |
| Location: West University of Timisoara (Advanced Environmental Research Laboratories), Timisoara (Romania) |
| Link to event: http://gonanobiomat.eu/results/workshops/ |
| Title of the presented work: Drug release from chitosan nanoparticles |
| List of authors: Daniela Dascălu, Alexandru Pahomi, Beatrice Vlad-Oros |
| Title of scientific event: BioNanoMaterials used in medical applications |
| Period: 21 March 2019 |
| Location: West University of Timisoara (Advanced Environmental Research Laboratories), Timisoara (Romania) |
| Link to event: http://gonanobiomat.eu/results/workshops/ |
| Title of the presented work: Prediction of the toxicity of 3-hydroxy-butyrate and 3-hydroxy-butyrate-co-3-hydroxyvalerat oligomers on humans and the environment |
| List of authors: Diana Larisa Roman, Marin Roman, Vasile Ostafe, Adriana Isvoran |
| Title of scientific event: BioNanoMaterials used in medical applications |
| Period: 21 March 2019 |
| Location: West University of Timisoara (Advanced Environmental Research Laboratories), Timisoara (Romania) |
| Link to event: http://gonanobiomat.eu/results/workshops/ |
| Title of the presented work: Applications of nanobiomaterials in medicine and the risk of toxicity on organisms |
| List of authors: Constantina Bianca Vulpe, Vasile Ostafe |
| Title of scientific event: BioNanoMaterials used in medical applications |
| Period: 21 March 2019 |
| Location: West University of Timisoara (Advanced Environmental Research Laboratories), Timisoara (Romania) |
| Link to event: http://gonanobiomat.eu/results/workshops/ |
| Title of the presented work: Current methodology on testing the manufactured nanomaterials using microorganisms standardized tests |
| List of authors: Adina Matica, Vasile Ostafe |
| Title of scientific event: BioNanoMaterials used in medical applications |
| Period: 21 March 2019 |
| Location: West University of Timisoara (Advanced Environmental Research Laboratories), Timisoara (Romania) |
| Link to event: http://gonanobiomat.eu/results/workshops/ |
| Title of the presented work: Assessment of the environmental effects of oligomers resulted from the degradation of polyhydroxyalkanoates and polylactic acid |
| List of authors: Marin Roman, Diana Larisa Roman, Daniela Dascalu, Vasile Ostafe, Adriana Isvoran |
| Title of scientific event: BioNanoMaterials used in medical applications |
| Period: 21 March 2019 |
| Location: West University of Timisoara (Advanced Environmental Research Laboratories), Timisoara (Romania) |
| Link to event: http://gonanobiomat.eu/results/workshops/ |
| Title of the presented work: Ecotoxicity of biopolymers with medical applications. Case study: chitosan, alginate and carboxymethyl cellulose |
| List of authors: Bianca-Vanesa Boros, Maria-Doriana-Otilia Ciosici, Elena-Roxana Vilceanu, Vasile Ostafe |
| Title of scientific event: BioNanoMaterials used in medical applications |
| Period: 21 March 2019 |
| Location: West University of Timisoara (Advanced Environmental Research Laboratories), Timisoara (Romania) |
| Link to event: http://gonanobiomat.eu/results/workshops/ |
| Title of the presented work: A high efficiency transformation method of yeast cells by electroporation, using chitosan nanomaterials |
| List of authors: Gheorghita Menghiu, Vasile Ostafe |
| Title of scientific event: 506th International Conference on Engineering and Natural Sciences (ICENS) |
| Period: 21-22 November 2018 |
| Location: Venice, Italy |
| Link to event: http://theires.org/Tentativeprogramme.php |
| Title of the presented work: Computational assessment of the pharmacokinetic profiles and environmental effects of poly L-lactate, poly(3-hydroxybutyrate) and poly(3-hydroxyvalerate) oligomers |
| List of authors: Vasile OSTAFE, Diana Larisa ROMAN, Marin ROMAN, Adriana ISVORAN |
| Title of scientific event: 15th National Conference of the Romanian Society of Pure and Applied Biophysics |
| Period: 7 – 10 September 2018 |
| Location: Bucharest, Romania |
| Link to event: http://www.biophysicsnet.ro/conference-programme/ |
| Title of the presented work: Computational evaluation of the environmental toxicity of poly L-lactate, poly(3-hydroxybutyrate) and poly(3-hydroxyvalerate) small oligomers |
| List of authors: Alecu CIORSAC, Daniela DASCĂLU, Diana Larisa ROMAN, Marin ROMAN, Vasile OSTAFE, Adriana ISVORAN |
| Title of scientific event: 15th National Conference of the Romanian Society of Pure and Applied Biophysics |
| Period: 7 – 10 September 2018 |
| Location: Bucharest, Romania |
| Link to event: http://www.biophysicsnet.ro/conference-programme/ |
| Title of the presented work: Computational assessment of the pharmacological profiles of chitin and chitosan small oligomers |
| List of authors: Diana Larisa ROMAN, Mădălina FILIP, Marin ROMAN, Vasile OSTAFE, Adriana ISVORAN |
| Title of scientific event: Annual International Conference of the Society of Biochemistry and Molecular Biology |
| Period: 5 – 7 September 2018 |
| Location: Bucharest, Romania |
| Link to event: http://www.biochim.ro/events/2018/Program-SRBBM2018.pdf |
| Title of the presented work: Computational Predictions of Pharmaceutical Profiles of Poly Lactic Acid and Polyhydroxybutyrate Small Oligomers |
| List of authors: Marin ROMAN, Diana Larisa ROMAN, Silvana CEAURANU, Vasile OSTAFE, Adriana ISVORAN |
| Title of scientific event: Annual International Conference of the Society of Biochemistry and Molecular Biology |
| Period: 5 – 7 September 2018 |
| Location: Bucharest, Romania |
| Link to event: http://www.biochim.ro/events/2018/Program-SRBBM2018.pdf |
| Title of the presented work: Computational Assessment of the Environmental Toxicity of some Polymers used as Pharmaceutical Excipients |
| List of authors: Marin ROMAN, Mădălina FILIP, Diana Larisa ROMAN, Vasile OSTAFE, Adriana ISVORAN |
| Title of scientific event: 7th IAPC Meeting & PFC-J |
| Period: 28 – 30 August 2018 |
| Location: Osaka, Japan |
| Link to event: https://www.iapchem.org/images/iapc-7/Book_of_%20abstracts.pdf |
| Title of the presented work: Molecular weight dependence of the ADME-Tox properties of some poly(3-hydroxybutyrate), poly(3-hydroxyvalerate) and poly(3-hydroxybutirate-co-3-hydroxyvalerate) oligomers |
| List of authors: Adriana ISVORAN, Alecu CIORSAC, Diana Larisa ROMAN, Marin ROMAN, Vasile OSTAFE |
| Title of scientific event: 18th European Congress On Biotechnology |
| Period: 2-4 July 2018 |
| Location: Geneve, Switzerland |
| Link to event: |
| Title of the presented work: http://www.ecb2018.com https://fems-microbiology.org/opportunities/18th-european-congress-biotechnology/ |
| List of authors: Giuseppe PERALE |
| Title of scientific event: Symposium of Chemistry Students from the Department of Biology and Chemistry (Faculty of Chemistry, Biology, Geography, West University of Timisoara) |
| Period: 26 June 2018 |
| Location: Timișoara, România |
| Link to event: |
| Title of the presented work: Chitosan based hydrogels with clinical applications |
| List of authors: Nicoleta SĂCULȚEANU, Daniela DASCĂLU, Beatrice VLAD – OROS |
| Title of scientific event: Symposium of Chemistry Students from the Department of Biology and Chemistry (Faculty of Chemistry, Biology, Geography, West University of Timisoara) |
| Period: 26 June 2018 |
| Location: Timișoara, România |
| Link to event: |
| Title of the presented work: Analysis of possible toxicity of chitosan oligomers on the human body |
| List of authors: Mădălina FILIP, Vasile OSTAFE, Adriana ISVORAN |
| Title of scientific event: Symposium of Chemistry Students from the Department of Biology and Chemistry (Faculty of Chemistry, Biology, Geography, West University of Timisoara) |
| Period: 26 June 2018 |
| Location: Timișoara, România |
| Link to event: |
| Title of the presented work: Computational assessment of ADME-Tox profile of polylactic acid |
| List of authors: Silvana CEAURANU, Adriana ISVORAN |
| Title of scientific event: WORKSHOP Green Nanochemistry – application of the safe-to-design principle for obtaining new nanomaterials |
| Period: 7 June 2018 |
| Location: Timișoara, România |
| Link to event: |
| Title of the presented work: Preparation and characterization of nano chitosan |
| List of authors: Alexandru PAHOMI, Beatrice VLAD-OROS, Daniela DASCĂLU |
| Title of scientific event: WORKSHOP Green Nanochemistry – application of the safe-to-design principle for obtaining new nanomaterials |
| Period: 7 June 2018 |
| Location: Timișoara, România |
| Link to event: |
| Title of the presented work: Environmental impact of nanoparticles: effect on soil and water microorganisms |
| List of authors: Adina MATICA, Vasile OSTAFE |
| Title of scientific event: WORKSHOP Green Nanochemistry – application of the safe-to-design principle for obtaining new nanomaterials |
| Period: 7 June 2018 |
| Location: Timișoara, România |
| Link to event: |
| Title of the presented work: Safety assessment of poly (3-hydroxybutyrate) small oligomers |
| List of authors: Diana Larisa ROMAN, Marin ROMAN, Silvana CEAURANU, Vasile OSTAFE, Adriana ISVORAN |
| Title of scientific event: WORKSHOP Green Nanochemistry – application of the safe-to-design principle for obtaining new nanomaterials |
| Period: 7 June 2018 |
| Location: Timișoara, România |
| Link to event: |
| Title of the presented work: Ecotoxicology test at enzymatic level. Chromatography and spectrophotometer analysis for invertase, sulphatase and acid phosphatase |
| List of authors: Bianca Constantina VULPE, Monica GUSA, Silviu COTREANȚI, Andra PANDELE, Vasile OSTAFE |
| Title of scientific event: WORKSHOP Green Nanochemistry – application of the safe-to-design principle for obtaining new nanomaterials |
| Period: 7 June 2018 |
| Location: Timișoara, România |
| Link to event: |
| Title of the presented work: Computational assessment of ADME-Tox profiles of some polylactic acid oligomers |
| List of authors: Marin ROMAN, Diana Larisa ROMAN, Silvana CEAURANU, Vasile OSTAFE, Adriana ISVORAN |
| Title of scientific event: WORKSHOP Green Nanochemistry – application of the safe-to-design principle for obtaining new nanomaterials |
| Period: 7 June 2018 |
| Location: Timișoara, România |
| Link to event: |
| Title of the presented work: Ecotoxicity of nanomaterials in the aquatic and terrestrial environments |
| List of authors: Bianca – Vanesa BOROȘ, Vasile OSTAFE |
| Title of scientific event: WORKSHOP Green Nanochemistry – application of the safe-to-design principle for obtaining new nanomaterials |
| Period: 7 June 2018 |
| Location: Timișoara, România |
| Link to event: |
| Title of the presented work: The exposure effect of organisms to nanoparticles and nanomaterials: genetic and epigenetic modifications |
| List of authors: Gheorghița MENGIU, Vasile OSTAFE |
| Title of scientific event: WORKSHOP Green Nanochemistry – application of the safe-to-design principle for obtaining new nanomaterials |
| Period: 7 June 2018 |
| Location: Timișoara, România |
| Link to event: |
| Title of the presented work: A computational approach of the concept of safe by design. Application for chitin and chitosan oligomers |
| List of authors: Mădălina FILIP, Miruna GUG, Vasile OSTAFE, Adriana ISVORAN |
| Title of scientific event: WORKSHOP Green Nanochemistry – application of the safe-to-design principle for obtaining new nanomaterials |
| Period: 7 June 2018 |
| Location: Timișoara, România |
| Link to event: |
| Title of the presented work: Safe by Design Principle |
| List of authors: Vasile OSTAFE |
| Title of scientific event: „BIOLOGY Annual Conference”, XI Edition, “Biological Processes – theoretical aspects and practical applications” |
| Period: 25 May 2018 |
| Location: Timișoara, România |
| Link to event: |
| Title of the presented work: ADME-Tox analysis of chitin and chitosan oligomers |
| List of authors: Mădălina FILIP, Vasile OSTAFE, Adriana ISVORAN |
| Title of scientific event: Nano-modeling of Strategic Materials for the Knowledge Economy (NANO-MOD) |
| Period: 16 – 17 May 2018 |
| Location: Timișoara, România |
| Link to event: https://doctorat.uvt.ro/wp-content/uploads/2018/03/2018-Edition-I_nano-mod_Timisoara-WUT-_Invitation_First-Circular_.pdf |
| Title of the presented work: Prediction of ADME-Tox properties of polylactic acid oligomers |
| List of authors: Diana Larisa ROMAN, Marin ROMAN, Silvana CEAURANU, Vasile OSTAFE, Adriana ISVORAN |
| Title of scientific event: Nano-modeling of Strategic Materials for the Knowledge Economy (NANO-MOD) |
| Period: 16 – 17 May 2018 |
| Location: Timișoara, România |
| Link to event: https://doctorat.uvt.ro/wp-content/uploads/2018/03/2018-Edition-I_nano-mod_Timisoara-WUT-_Invitation_First-Circular_.pdf |
| Title of the presented work: Molecular weight dependence of ADME-Tox properties of chitin and chitosan oligomers |
| List of authors: Madalina FILIP, Vasile OSTAFE, Adriana ISVORAN |
| Title of scientific event: 9th International Congress Nanotechnology in Biology & Medicine – BioNanoMed 2018 |
| Period: 25-27 April 2018 |
| Location: Graz, Austria |
| Link to event: https://www.americanelements.com/9th-international-congress-nanotechnology-in-biology-medicine-bionanomed-2018 |
| Title of the presented work: |
| List of authors: Gerrit BORCHARD |
| Title of scientific event: XII Spanish-Portuguese Conference on Controlled Drug Delivery – Tailoring drug delivery systems to the patients’ needs |
| Period: 14-16 January 2018 |
| Location: Coimbra, Portugal |
| Program of the event: https://www.splc-crs.org/meeting-2018/; https://www.splc-crs.org/meeting-2018/docs/AbstractBook2018.pdf |
| Title of the presented work: GoNanoBioMat Project – Polymeric NanoBioMaterials for drug delivery: developing and implementation of safe-by-design concept enabling safe healthcare solutions |
| List of authors: S. Jesus, P. Marques, O. Borges, M. Zinn, G. Borchard, C. Som, G. Perale, P. Frei, U. Laubscher, V. Ostafe, Y. Popowski and P. Wick |
| Title of scientific event: National conference RoMedINF 2017 „E-Health for Smart Cities” |
| Period: 23 – 24 November 2017 |
| Location: Timisoara, ROMANIA |
| Program of the event: http://www.srimed.ro/ |
| Title of the presented work: Analysis of the influence of size of chitin and chitosan molecules on their pharmacokinetic profiles and environmental toxicity |
| List of authors: Mădălina FILIP, Adriana ISVORAN |
| Title of scientific event: Nanosafety 2017 |
| Period: 11-13 October 2017 |
| Location: Saarbrücken, Germany |
| Link to event: http://www.nanosafety2017.de/ |
| Title of the presented work: |
| List of authors: Mélanie SCHMUTZ |
| Title of scientific event: CCMX_MARVEL Annual Meeting |
| Period: 5 October 2017 |
| Location: Dübendorf, Switzerland |
| Link to event: http://www.ccmx.ch/courses-and-events/article/2017/02/ccmx-marvel-materials-dayccmx-annual-meeting/ |
| Title of the presented work: |
| List of authors: WICK Peter |
| Title of scientific event: 6th World Conference on Physico Chemical Methods in Drug Discovery and 3rd World Conference on ADMET and DMPK |
| Period: 4 – 6 September 2017 |
| Location: Zagreb, CROATIA |
| Program of the event: http://www.iapchem.org/page.php?page_id=89 |
| Title of the presented work: ADME-Tox profiling of some water soluble chitosan derivatives used to obtain nanomaterials |
| List of authors: Adriana ISVORAN, Alecu CIORSAC, Vasile OSTAFE |
| Title of scientific event: 19th International Union for Pure and Applied Biophysics Congress (IUPAB) & 11th European Biophysics Congress and 11th European Biophysics Congress (EBSA) |
| Period: 16 – 25 June 2017 |
| Location: Edinburgh, SCOTLAND |
| Program of the event: http://www.iupab2017.org/programme |
| Title of the presented work: Prediction of Biochemical Mechanisms of Action and Side-Effects of the Anabolic Steroids |
| List of authors: Diana-Larisa ROMAN, Marin ROMAN, Alecu CIORSAC, Adina MATICA, Vasile OSTAFE, Adriana ISVORAN |
| Title of scientific event: The Annual International Conference Romanian Society for Biochemistry & Molecular Biology |
| Period: 8 – 9 June 2017 |
| Location: Timisoara, ROMANIA |
| Program of the event: http://www.srbbm-banat.ro/meetings-events/annual-meeting |
| Title of the presented work: Preliminary results of an enzymatic test battery development for the assessment of toxicity of biopolymers |
| List of authors: Bianca – Vanesa BOROS, Maria – Doriana – Otilia CIOSICI, Elena-Roxana VILCEANU, Vasile OSTAFE |
| Title of scientific event: The Annual International Conference Romanian Society for Biochemistry & Molecular Biology |
| Period: 8 – 9 June 2017 |
| Location: Timisoara, ROMANIA |
| Program of the event: http://www.srbbm-banat.ro/meetings-events/annual-meeting |
| Title of the presented work: Computational assessment of the pharmacokinetics properties of some water soluble chitosan derivatives |
| List of authors: Adriana ISVORAN, Mădălina FILIP, Alecu CIORSAC, Vasile OSTAFE |
| Title of scientific event: Designer Biology: from proteins and cells to scaffolds and materials |
| Period: 7-9 June 2017 |
| Location: Vienna, Austria |
| Link to event: http://www.efb-central.org/index.php/DesignerBiology/ |
| Title of the presented work: |
| List of authors: Manfred ZINN |
| Title of scientific event: Swiss NanoConvention 2017 |
| Period: 1-2 June 2017 |
| Location: Fribourg, Switzerland |
| Link to event: http://swissnanoconvention.ch/2017/ |
| Title of the presented work: |
| List of authors: Peter WICK |
| Title of scientific event: 8th Intern. Congress Nanotechnology in Medicine & Biology |
| Period: 20-22 March 2017 |
| Location: Krems, Austria |
| Link to event: http://www.bionanomed.at/
https://www.bionanonet.at/images/BioNanoMed_2017_First_Announcement_2.pdf |
| Title of the presented work: Safe-by-Design an Interdiciplinary Challenge Facilitating Nanomedical Applications |
| List of authors: Wick Peter, Inge K Herrmann |